Microsoft (NASDAQ: MSFT ) took a break from shooting itself in the foot to announce some much-needed updates to the Windows 8 operating system. Windows division CMO and CFO Tami Reller took pains to explain that the company must have a point of view and basically stick to its guns.
Microsoft is trying to revive the flagging PC market by making desktops more like tablets, but isn’t that a completely backwards strategy? The company touts 1.3 billion global customers, all of whom expect a certain experience on their traditional computer systems. And Microsoft just keeps pushing that carrot out of reach.
In the video below, Fool contributor Anders Bylund explains the move to investors.
It’s been a frustrating path for Microsoft investors, who’ve watched the company fail to capitalize on the incredible growth in mobile over the past decade. However, with the release of its own tablet, along with the widely anticipated Windows 8 operating system, the company is looking to make a splash in this booming market. In a new premium report on Microsoft, a Motley Fool analyst explains that while the opportunity is huge, so are the challenges. The report includes regular updates as key events occur, so make sure to claim a copy of this report now by clicking here.
10 Best Performing Stocks To Watch For 2015: Spdr S&P Homebuilders Etf (XHB)
SPDR S&P Homebuilders ETF (the Fund) seeks to replicate as closely as possible, before expenses, the performance of the S&P Homebuilders Select Industry Index (the Index). To accomplish this, the Fund utilizes a passive or indexing approach and attempts to approximate the investment performance of its Index, by investing in a portfolio of stocks intended to replicate the Index.
The S&P Homebuilders Select Industry Index seeks to provide a representation of the homebuilders’ sub-industry portion of the S&P Total Market Index. The S&P TMI tracks all the United States common stocks regularly traded on the NYSE, American Stock Exchange, NASDAQ National Market and NASDAQ Small Cap Exchanges. The Homebuilders Index is an equal weighted market cap index.
- [By Anora Mahmudova]
The day’s economic data provided a little support. The sales pace of existing homes ticked down in March to the slowest rate since July 2012, according to data released Tuesday, however the decline was smaller than the consensus rate forecast by economists polled by MarketWatch. The SPDR S&P Homebuilder ETF (XHB) gained 1%.
- [By Jon C. Ogg]
1. The U.S. economy grows 3% as housing starts surpass one million and private employment hits an all-time high – All time high on private employment? 1 million housing starts?
Homebuilder ETF: SPDR S&P Homebuilders ETF (NYSEArca: XHB) as it is tied to homebuilders and building products rather than including other sectors that only overlap in building. At $32.57, its 52-week range is 426.94 to $33.38. Housing Starts were always well over 1 million on an annualized basis each month before the recession, but they only reached that in two months of 2013 (St. Louis Fed data).
2. 10-Year Treasury yields move toward 3.5% as the Federal Reserve completes tapering and holds short-term rate near zero – This may sound bad, but it is actually good and fits in line with rates not rising too much. Keep in mind that the 10-year Treasury is at 2.94% now and ended at 3.03% on the last day of 2013. Elsewhere on the yield curve, Doll sees many parts of the fixed income market to end 2014 with negative total rates of return.
- [By John Maxfield]
Meanwhile, housing is feeling the effects via higher mortgage rates. For portions of last year, a 30-year conventional mortgage carried an interest rate of less than 3.5%. Since the Fed’s announcements, the same rate has climbed back to more than 4%. This is sending shivers through homebuilders’ stocks, as the net effect is to make homes more expensive. The SPDR S&P Homebuilders (NYSEMKT: XHB ) ETF, which tracks the housing sector, is down almost 9% since May 22.
10 Best Performing Stocks To Watch For 2015: Digital Power Corp (DPW)
Digital Power Corporation (Digital), incorporated in 1969, is a solution-driven organization that designs, develops, manufactures and sells high-grade customized and flexible power system solutions for the demanding applications in the medical, military, telecom and industrial markets. It also has a wholly owned subsidiary, Digital Power Limited (DPL), which operates under the brand name of Gresham Power Electronics (Gresham). DPL is located in Salisbury, England, and it designs, manufactures and sells power products and system solutions mainly for the European marketplace, including power conversion, power distribution equipment, direct current/active current (DC/AC) inverters and uninterrupted power supply (UPS) products. DPL’s defense business has specialists in the field of naval applications of power distribution conversion. It markets and sells its products to many diverse market segments, including the telecom, industrial, medical and military/defense industries. Its products serve a global market, with an emphasis on North America and Europe. The Company offers a product variety, including a full custom product design and production, high-speed switching power front-end, modified-standard and value added products, open-frame, Compact-PCI, ATSC front-ends and power over Ethernet (PoE) product solutions, providing power output from 50 to 24,000 watts. On June 16, 2011 the Company has acquired Telkoor Telecom Ltd.
Power System Solutions
The Company provides custom power system solutions, high-grade flexibility series power supply products and value-added services to diverse industries and markets, including military/defense, telecom, medical and industrial. It provides high-grade custom power system solutions to numerous customers in multiple industry segments. Each custom solution that it develops is based on high power density and a special layout to meet each of its customer’s operation environments where efficiency, size and performance are key.
Di! gital Power Limited (Gresham Power Electronics)
DPL designs, manufactures, and distributes switching power supplies, uninterruptible power supplies, and power conversion and distribution equipment frequency converters for the commercial and military markets, under the name Gresham. Frequency converters manufactured by Gresham are used by navel warships to convert their generated 60-cycle electricity supply to 400 cycles. This 400-cycle supply is used to power their critical equipment such as gyro, compass, and weapons systems. Gresham also designs and manufactures transformer rectifiers for naval use. Typically, these provide battery supported back up for critical DC systems, such as machinery and communications. In addition, higher power rectifiers are used for the starting and servicing of helicopters on naval vessels, and Gresham supplies these as part of overall helicopter start and servicing systems.
The Company competes with Power-One, Emerson (Astec) Technologies, Inc., Lambda Electronics, and Mean-Well Power Supplies.
- [By Robert Wall]
One of the country’s largest employers with more than 150,000 staff, Royal Mail has shifted away from letters to more lucrative package shipping, competing with TNT Express NV (TNTE) of the Netherlands and Deutsche Post AG (DPW)’s DHL Express.
10 Best Performing Stocks To Watch For 2015: comScore Inc.(SCOR)
comScore, Inc. provides a range of digital analytics solutions primarily in the United States, Europe, and Canada. The company offers its customers with information regarding usage of their online properties and those of their competitors, coupled with information on consumer demographic characteristics, attitudes, lifestyles, and offline behavior solutions through its digital media measurement platforms. Its digital media measurement platforms consist of proprietary databases and a computational infrastructure that measures, analyzes, and reports on digital activity. The company also provides audience analytics tools that measure the size, behavior, and characteristics of Internet users on PCs, mobile devices, and tablets, as well as insight into online advertising; and advertising analytics products, such as AdEffx, Media Planner 2.0, and Campaign Essentials, which provide solutions for developing, executing, and evaluating online advertising campaigns, as well as valida ted campaign essentials that provide intelligence regarding validated impressions. In addition, it offers Web analytics products and solutions, as well as Web analytics platform that integrates data from multiple sources, including Web, mobile, video, and social media interactions; and mobile and network analytics products, such as comprehensive market intelligence and network solutions to mobile carriers with information on network optimization and capacity planning, customer experience, and market intelligence. The company serves Internet service providers, investment banks, media and digital agencies, consumer banks, wireless carriers, pharmaceutical makers, credit card issuers, and consumer packaged goods companies. comScore, Inc. was founded in 1999 and is headquartered in Reston, Virginia.
- [By Paul Ausick]
The data comes from the latest report on the U.S. smartphone market from comScore Inc. (NASDAQ: SCOR).
On the operating system (platform) front, Apple gained 1.2% share in the three-month period to post a total of 41.8% of the platform market. Google Inc.’s (NASDAQ: GOOG) lost 0.3% share during the period, but continues to hold over half the platform market, with a 51.5% share. BlackBerry Ltd. (NASDAQ: BBRY) dropped 0.4% to post a 3.4% share, while Microsoft Corp. (NASDAQ: MSFT) lost 0.2% to post a 3.1% share.
- [By DAILYFINANCE]
Ross D. Franklin/APAmazon.com employee Hugh Johnson Jr. packs up a box at an Amazon.com warehouse earlier this month. Americans waited until the last minute to buy holiday gifts, but retailers weren’t prepared for the spike in sales. Heavy spending in the final days of the mostly lackluster season sent sales up 3.5 percent between Nov. 1 and Tuesday, according to MasterCard Advisors SpendingPulse, which tracks payments but doesn’t give dollar figures. Online shopping led the uptick, with spending up 10 percent to $38. 91 billion between Nov. 2 and Sunday, research firm ComScore (SCOR) said. “We always have last-minute Charlies, but this year even people who normally complete shopping earlier completed shopping later,” said Marshal Cohen, chief retail analyst at market research firm NPD Group. The late surge caught companies off guard. UPS (UPS) and FedEx (FDX) failed to deliver some packages by Christmas due to a combination of poor weather and overloaded systems, leaving some unhappy holiday shoppers. Justin Londagin and his wife ordered their 7-year-old son a jersey of Russell Wilson of the Seattle Seahawks from NFL’s website on Dec. 19. They paid $12.95 extra for two-day shipping to get it to their Augusta, Kan., home before Christmas, but it didn’t arrive in time. “We had to get creative and wrote him a note from Santa to tell him that the jersey fell out of the sleigh and Santa will get it to him as soon as he could,” he said. Amazon.com (AMZN) is offering customers with delayed shipments a refund on their shipping charges and $20 toward a future purchase. And other retailers such as Macy’s said they are looking into the situation. The last-minute surge this year solidifies the increasing popularity of online shopping, which accounts for about 10 percent of sales during the last three months of the year. It also underscores the challenges that companies face delivering on the experience, particularly during the holiday shopping season that runs
- [By Douglas A. McIntyre]
Methodology: comScore, Inc. (NASDAQ: SCOR), a leader in measuring the digital world, today released its monthly ranking of U.S. desktop web activity at the top online properties for November 2013 based on data from the comScore Media Metrix service
10 Best Performing Stocks To Watch For 2015: FCCC Inc (FCIC)
FCCC, Inc. (FCCC), incorporated on March 21, 1960, is focused on merger, acquisition, reverse merger or a business transaction opportunity with an operating business or other financial transaction. The Company has not restricted its search to any particular business, industry or geographical location.
As of March 31, 2013, the Company had no arrangements or understandings with respect to any merger, acquisition, reverse merger or business combination candidate. The Company has limited operations and is actively seeking merger, reverse merger, acquisition or business combination opportunities with an operating business or other financial transaction opportunities.
- [By The Science of Hitting]
After the financial crisis, the Financial Crisis Inquiry Commission (FCIC) was created to determine the root cause of the crisis; as part of that effort, the commission was required to make the ensuing interviews of hedge fund managers, bankers, and economists available to the public. One of the people interviewed was Warren Buffett, and as expected, he didn’t disappoint. During the interview, he was asked to discuss the difference between investment and speculation; here was his response (bold added for emphasis):
10 Best Performing Stocks To Watch For 2015: TC PipeLines LP (TCP)
TC PipeLines, LP (the Partnership), incorporated on December 16, 1998, acquires, owns and participates in the management of energy infrastructure businesses in North America. The Company’s pipeline systems transport natural gas in the United States. The Partnership is managed by the Company’s General Partner, which is an indirect, wholly-owned subsidiary of TransCanada. The Company has equity ownership interests in four natural gas interstate pipeline systems. The Company’s pipeline systems include Great Lakes, Northern Border, GTN, Bison, North Baja and Tuscarora. The Company owns 46.45% interest in Great Lakes. Great Lakes connect with the TransCanada Mainline at the Canadian border near Emerson, Manitoba, Canada and St. Clair, Michigan, near Detroit. Great Lakes are a bi-directional pipeline that can receive and deliver natural gas at multiple points along its system. In July 2013, TC PipeLines, LP announced the closing of its acquisition of an additional 45% inte rest in each of Gas Transmission Northwest LLC (GTN) and Bison Pipeline LLC (Bison) from subsidiaries of TransCanada Corporation.
The Company owns 50% interest in Northern Border. Northern Border Extends between the Canadian borders near Port of Morgan, Montana to a terminus near North Hayden, Indiana, south of Chicago. Northern Border is capable of receiving natural gas from Canada, the Williston Basin and Rockies Basin. The Company owns 25% interest in GTN. GTN extends between an interconnection near Kingsgate, British Columbia, Canada at the Canadian Border to a point near Malin, Oregon at the California border. The Company owns 25% interest Bison. Bison extends from a location near Gillette, Wyoming to Northern Border’s pipeline system in North Dakota. The Company owns 100% interest in North Baja. North Baja extends between an interconnection with the El Paso Natural Gas Company pipeline near Ehrenberg, Arizona to an interconnection with a natural gas pipel ine near Ogilby, California on the Mexican border. The Compa! ny owns 100% interest in Tuscarora. Tuscarora extends between GTN near Malin, Oregon to its terminus near Reno, Nevada and delivers natural gas in northeastern California and northwestern Nevada.
- [By Robert Rapier]
Next week’s issue will tackle the three remaining questions: one on MLP equivalents in Canada and Australia, one on Enbridge Energy Partners (NYSE: EEP) and TC Pipelines (NYSE: TCP), and a third query on Access Midstream Partners (NYSE: ACMP), Crestwood Midstream Partners (NYSE: CMLP) and Mid-Con Energy Partners (Nasdaq: MCEP).
- [By Rich Duprey]
For holders of TCF Financials’ (NYSE: TCP ) non-convertible perpetual 7.5% Series A stock, the board of directors announced yesterday investors will receive $0.05 per share on August 30 to holders of record at the close of business on August 15.
10 Best Performing Stocks To Watch For 2015: Koninklijke Ahold NV (AHONY)
Koninklijke Ahold N.V. (Ahold), incorporated on April 29, 1920, is engaged in the operation of retail food stores in the United States and Europe through subsidiaries and joint ventures. Ahold’s retail operations are presented in four segments: Stop & Shop/Giant-Landover, Giant-Carlisle, Albert Heijn and Albert/Hypernova. During the fiscal year ended January 3, 2010 (fiscal 2009), it operated 2,909 stores. On February 8, 2010, Ahold’s Giant-Carlisle acquired 25 stores from Ukrop’s Super Markets.
Franchisees operated 783 of the Albert Heijn, Etos and Gall & Gall stores, 463 of which were either owned by the franchisees or leased independently from Ahold. Of the 2,446 stores, 20% were company-owned and 80% were leased. Ahold’s stores range in size from 20 to over 10,000 square meters. Albert Heijn is a food retailer in the Netherlands. Etos is a health and beauty retailer in the Netherlands. Gall & Gall is a wine and liquor specialist in the Netherlands. Stop & Shop is a supermarket brand, operating in six states in the northeast United States. Giant-Landover is a supermarket brand, operating in four states in the mid-Atlantic United States. Peapod is an online grocery delivery service working in partnership with Stop & Shop and Giant-Landover. It also serves the metropolitan areas of Chicago, Illinois; Milwaukee and Madison, Wisconsin, and the northern areas of Indiana.
- [By Rich Duprey]
As mentioned, Kroger is still swallowing Harris Teeter and has said it needs time to make more acquisitions. Royal Ahold (NASDAQOTH: AHONY ) is also said to be leery about doing large acquisitions these days, while Cerberus recently finished acquiring the Albertsons and Acme chains from SUPERVALU (NYSE: SVU ) for $3.3 billion.
10 Best Performing Stocks To Watch For 2015: URS Corporation(URS)
URS Corporation provides engineering, construction, and technical services to the power, infrastructure, federal, and industrial and commercial market sectors in the United States and internationally. Its services for power sector include planning, designing, engineering, constructing, retrofitting, and maintaining a range of power-generating facilities; and the systems that transmit and distribute electricity, as well as the development and installation of clean air technologies that reduce emissions at fossil fuel power plants. The company?s services for infrastructure sector comprise program management, planning, architect, engineering, general contracting, construction, and construction management for surface, air, and rail transportation networks; ports and harbors; and water supply, and treatment and conveyance systems. Its services for federal sector consist of program management; planning, design, and engineering; systems engineering and technical assistance to con struction and construction management; operations and maintenance; and decommissioning and closure primarily for the United States federal government and national governments of other countries. URS Corporation?s services for industrial and commercial sector include front-end studies, engineering and process design, procurement, construction and construction management, facility management, and operations and maintenance, as well as due diligence, permitting, compliance, environmental management, pollution control, health and safety, waste management, and hazardous waste remediation. The company was formerly known as Broadview Research Corporation and changed its name to URS Corporation in 1976. URS Corporation was founded in 1904 and is headquartered in San Francisco, California.
- [By Maria Armental var popups = dojo.query(“.socialByline .popC”); popups.forEach]
URS Corp.’s(URS) first-quarter earnings slumped 63% on a sharp drop in revenue related to some government contracts that the engineering company is winding down. Shares fell 7.1% to $43.85 premarket.
- [By Ben Levisohn]
URS Corp. (URS) has plunged 7.1% to $43.85 after its profit of 37 cents a share missed the Street consensus by 30 cents.
Plug Power (PLUG) has dropped 3.7% to $3.94 after it reported a loss of 6 cents a share, missing analyst estimates for a loss of 5 cents.
- [By Monica Gerson]
URS (NYSE: URS) is projected to post its Q1 earnings at $0.68 per share on revenue of $2.68 billion.
LATAM Airlines Group SA (NYSE: LFL) is expected to post its Q1 earnings at $0.20 per share on revenue of $3.42 billion.
10 Best Performing Stocks To Watch For 2015: Genworth Financial Inc (GNW)
Genworth Financial, Inc., a financial security company, provides insurance, wealth management, investment, and financial solutions in the United States and internationally. The company offers various insurance and fixed annuity products, including life and long-term care insurance products; payment protection insurance products for consumers primarily to meet specified payment obligations; and wealth management products, such as managed account programs with advisor support and financial planning services. It also provides mortgage insurance products and related services to insure prime-based, individually underwritten residential mortgage loans or flow mortgage insurance; and mortgage insurance on a structured or bulk basis, as well as offers services, analytical tools, and technology that enable lenders to operate and manage risk. In addition, the company provides institutional products consisting of funding agreements, funding agreements backing notes, and guaranteed in vestment contracts. Genworth Financial, Inc. distributes its products and services through financial intermediaries, advisors, independent distributors, affinity groups, and sales specialists. The company was founded in 2003 and is headquartered in Richmond, Virginia.
- [By Henry Lee] Recent Posts: There’s Plenty to Like In Value Stocks Like Genworth (GNW) Apple’s Next Big Thing? Forget About It View All Posts
If the recent volatility in the market has you feeling uneasy, you’re not alone. That feeling in your gut means something. Listen to it.
- [By Mani]
[Related -Genworth Financial (GNW): This Hot Financial Stock Still Has 70% Upside]
The company could get additional capital in the following ways, which may be used for dividends and share repurchases.
- [By Sue Chang and Saumya Vaishampayan]
Genworth Financial Inc. (GNW) shares added 4%. The insurer on Wednesday said it plans to expand and restructure its sales team this year to better work with mortgage originators.
- [By Selena Maranjian]
The biggest new holdings are Joy Global, and Genworth Financial (NYSE: GNW ) . Other new holdings of interest include Linn Co (NASDAQ: LNCO ) , an oil-and-gas company with a dividend yield of 9.1%. It largely exists to own units of the master limited partnership Linn Energy and convert distributions into dividends. Linn and Linn Co recently acquired Berry Petroleum, and Linn is also building its position in the promising Permian Basin. Bulls like Linn’s cash generation and growth prospects. Bears have worried about operational mishaps and an SEC inquiry, but the inquiry has been fruitless. The stock has recently been upgraded by analysts at Robert W. Baird and Howard Weill.
10 Best Performing Stocks To Watch For 2015: Advanced Semiconductor Engineering Inc (ASX)
Advanced Semiconductor Engineering, Inc. is principally engaged in the manufacture, assembly, processing, testing and distribution of integrated circuits (ICs). The Company provides semiconductor packaging and testing services, including plastic leaded chip carriers (PLCCs), quad flat packages (QFPs) and flip chip packaging technology, among others, which are applied in the manufacture of household electrical appliances, communication devices, automobile components, personal computers, set top boxes, servers, memory integrated circuits (ICs), mobile phones, digital cameras, game consoles, projectors, high definition (HD) televisions, wireless communication network products and power management ICs, among others. The Company operates its businesses primarily in Taiwan, Europe and the Americas. In August 2010, the Company acquired a 100% interest in EEMS Test Singapore.
The Company is focused on packaging and testing logic semiconductors. The Company offers its customers turnkey services, which consist of packaging, testing and direct shipment of semiconductors to end users designated by its customers. The Company’s global base of over 200 customers includes semiconductor companies across a range of end use applications, including Altera Corporation, ATI Technologies, Inc., Broadcom Corporation, Cambridge Silicon Radio Limited and Microsoft Corporation. During the year ended December 31, 2008, the Company’s packaging revenues accounted for 77.7% of its net revenues and its testing revenues accounted for 20.1% of its net revenues.
The Company offers a range of package types to meet the requirements of its customers, with a focus on packaging solutions. Within its portfolio of package types, the Company focuses on the packaging of semiconductors. These include advanced leadframe-based package types, such as quad flat package, thin quad flat package, bump chip carrier and quad flat no -lead package, and package types based on substrates, such a! s flip-chip ball grid array (BGA) and other BGA types, as well as other packages, such as wafer-bumping products. Leadframe-based packages are packaged by connecting the die, using wire bonders, to the leadframe with gold wire. The Company’s leadframe-based packages include quad flat package (QFP)/ thin quad flat package (TQFP), quad flat no-lead package (QFN)/microchip carrier (MCC), advanced quad flat no-lead package (AQFN), bump chip carrier (BCC), small outline plastic package (SOP)/thin small outline plastic package (TSOP), small outline plastic j-bend package (SOJ), plastic leaded chip carrier (PLCC) and plastic dual in-line package (PDIP). Substrate-based packages employ the BGA design, which utilizes a substrate rather than a leadframe. It also assembles system-in-a-package products, which involve the integration of more than one chip into the same package. The Company’s substrate-based packages include Plastic BGA, Cavity Down BGA, Stacked-Die BGA, Flip-Chip BGA and land grid array (LGA).
The Company’s wafer-level packaging products include wafer level chip scale package (aCSP) and advanced wafer level package (aWLP). The Company offers module assembly services, which combine one or more packaged semiconductors with other components in an integrated module to enable functionality, typically using surface mount technology (SMT) machines and other machinery and equipment for system-level assembly. End use applications for modules include cellular phones, personal digital assistant (PDAs), wireless local area network (LAN) applications, bluetooth applications, camera modules, automotive applications and toys.
The Company provides module assembly services primarily at its facilities in Korea for radio frequency and power amplifier modules used in wireless communications and automotive applications. Interconnect materials connect the input/output on the semiconductor dies to the printed circuit board. Interc onnect materials include substrate, which is a multi-layer m! iniature ! printed circuit board. The Company produces substrates for use in its packaging operations.
The Company provides a range of semiconductor testing services, including front-end engineering testing, wafer probing, final testing of logic/mixed-signal/radio frequency (RF) and memory semiconductors and other test-related services. The Company provides front-end engineering testing services, including customized software development, electrical design validation, and reliability and failure analysis. The Company provides final testing services for a variety of memory products, such as static random access memory (SRAM), dynamic random access memory (DRAM), single-bit erasable programmable read-only memory semiconductors and flash memory semiconductors.
The Company provides a range of additional test-related services, including burn-in testing, module sip testing, dry pack, tape and reel, and electric interface board and mec hanical test tool design. The Company offers drop shipment services for shipment of semiconductors directly to end users designated by its customers.
- [By Jeff Reeves]
Best Stocks to Buy for Around $5: Advanced Semiconductor Engineering (ASX)
Advanced Semiconductor Engineering (ASX) builds and distributes integrated circuits and other electronics. While that’s not as sexy as other chipmakers that play to mobile, it’s still a good business, considering the general demand for microchips in everything from cars to computers to TVs.
- [By David Dittman]
Crown Resorts is a buy all the way up to USD16.50 on the Australian Securities Exchange (ASX) using the symbol CWN and on the US over-the-counter (OTC) market using the symbol CWLDF.
- [By Namitha Jagadeesh]
The FTSE 100 Index (UKX) fell 1.31 points, less than 0.1 percent, to 6,679.77 at 10:12 a.m. in London, trimming an earlier decline of as much as 0.6 percent. The gauge has climbed 13 percent this year as central banks maintained stimulus measures to support the global economy. The broader FTSE All-Share Index (ASX) was also little changed today, while Ireland’s ISEQ Index retreated 0.3 percent.
- [By Jeff Reeves]
Advanced Semiconductor Engineering (ASX) builds and distributes integrated circuits and other electronics. It’s not as sexy as some mobile chipmakers, but thankfully it doesn’t have to be — ASX is simply capitalizing on the general demand for microchips in everything from cars to computers to TVs.
10 Best Performing Stocks To Watch For 2015: Prothena Corporation PLC (PRTA)
Prothena Corporation PLC, incorporated on September 26, 2012, is an Ireland-based, clinical-stage biotechnology company. The Company is engaged in discovering and developing monoclonal antibodies that are directed towards misfolded proteins or improper cell adhesion. Its pipeline includes NEOD001, PRX002 and PRX003. The Company’s work in protein misfolding could result in therapies to treat several neurodegenerative diseases, including AL (primary) and AA (secondary) forms of amyloidosis (NEOD001), Parkinson’s disease and related synucleinopathies (PRX002). Its cell adhesion development activities could generate new therapies to treat inflammatory diseases and metastatic cancers (PRX003). The Company’s program, NEOD001, is in Phase 1. In addition to antibodies directed to neo-epitope targets, it is developing antibodies directed to other targets. The Company has generated antibodies against cell adhesion targets expressed on certain pathogenic Th17 immune cells and tum or cells.
The Company’s pipeline also includes several late discovery stage programs for which it is testing antibodies in preclinical models of disease. It is also generating additional antibodies against other targets involved in protein misfolding and cell adhesion for characterization in vivo and in vitro.
NEOD001 for Amyloidosis
NEOD001 is a monoclonal antibody that targets the amyloid that accumulates in both AL and AA forms of amyloidosis. The antibody was designed to not react with normal serum amyloid A and only with the aberrant cleaved form of the protein (amyloid A).
PRX002 for Parkinson’s Disease
The Company has generated antibodies targeting alpha-synuclein that may slow or reduce the neurodegeneration associated with synuclein misfolding and/or transmission. It has tested these antibodies in various cellular and animal models of synuclein-related disease. In a transgenic mouse model of Parkin son’s disease, passive immunization with 9E4, a murine ver! sion of PRX002, reduced the appearance of synuclein pathology, protected synapses and improved performance by the mice in behavioral testing. The humanized antibody product candidate PRX002 has advanced into manufacturing and preclinical testing.
PRX003 for Inflammatory Diseases and Cancers
The Company is developing PRX003, a monoclonal antibody targeting MCAM for the potential treatment of inflammatory diseases and cancers. It has generated monoclonal antibodies that block MCAM-mediated cell adhesion and have been shown to delay relapse and severity of relapse in a mouse model of multiple sclerosis known as experimental autoimmune encephalomyelitis. The Company’s antibodies are being tested in animal models of inflammatory diseases and cancers. Based on early results from these studies, it has identified a clinical candidate, PRX003. It has advanced this antibody into manufacturing and intends to advance this antibody into preclinical testing.Advisors’ Opinion:
- [By Jake L’Ecuyer]
Prothena Corporation (NASDAQ: PRTA) shares were down as well, falling 28.00 percent to $27.13 after the company released some materials from its coming symposium presentation.
- [By Jake L’Ecuyer]
Shares of Prothena Corporation plc (NASDAQ: PRTA) got a boost, shooting up 6.99 percent to $32.00 after the company reported the successful start of a Phase 1 clinical trial of PRX002 for the treatment of Parkinson’s disease. Citigroup initiated coverage on the stock with a Buy rating and a $50.00 price target.
- [By Jake L’Ecuyer]
Equities Trading UP
Prothena Corporation plc (NASDAQ: PRTA) shares shot up 21.60 percent to $45.19 after the company reported clinical data to be presented at International Symposium on Amyloidosis. Morgan Stanley raised the price target on the stock from $35.00 to $53.00.